D&PS – D&PS May 2025 Column
Dr. Chang-hwan Cho of Dong-An Joongsim Clinic contributed a column to the May 2025 issue of D&PS magazine titled: “Aesthetic Medicine Trends from 2017 to 2025
– How Energy-Based Devices Stimulate Adipocytes.”

-Column Content-
In recent aesthetic medicine, the focus has expanded beyond mere skin tightening to include precise modulation of adipocyte structure and function
using Energy-Based Devices (EBDs). Treatments such as radiofrequency (RF) and laser therapy induce controlled thermal elevation within the skin,
selectively stimulating adipose tissue while promoting collagen remodeling and fibrotic responses. Adipose tissues respond differently depending
on their regional collagen density and maturity. Moreover, components such as the dWAT (dermal White Adipose Tissue) layer, caveolae structures,
and the expression levels of caveolin-1 are closely associated with treatment outcomes. As aging progresses, caveolin-1 decreases, leading
to impaired wound healing and reduced regenerative capacity of the skin. Thus, it is essential to regulate this mechanism through appropriate EBD interventions.
Looking forward, aesthetic medicine is expected to focus on personalized energy-based strategies that comprehensively consider the skin’s electrical properties,
the microstructure of adipose tissue, and intercellular signaling.